I use my Ender 3 for PLA only, and my Ender 3 S1 for everything else. I'm a tinkerer and a learner so maybe other printers are better but I'm happy with them. I design and print a ton of stuff with them. Only real mods are a CR Touch for the Ender 3, all metal hot end plus abrasive nozzle for the S1, and custom tweaked marlin firmware for both.
Hoffman got me to switch from Cura to PrusaSlicer while doing the SL9 and I've never gone back. I'm still using Fusion though. I'm too cheap to buy expensive CAD software and I haven't been successful so far switching to Solid Edge. I'm just too comfortable and experienced with Fusion. I hate that it's cloud based though.